EXO1, exonuclease 1, 9156

N. diseases: 87; N. variants: 22
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4149909
rs4149909
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0206710
Disease:
Basal Cell Neoplasm
G 0.700 GeneticVariation GWASCAT Combined analysis of keratinocyte cancers identifies novel genome-wide loci. 31174203 2019
dbSNP: rs4149909
rs4149909
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0751676
Disease:
Basal Cell Cancer
G 0.700 GeneticVariation GWASCAT Combined analysis of keratinocyte cancers identifies novel genome-wide loci. 31174203 2019
dbSNP: rs4149909
rs4149909
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0007117
Disease:
Basal cell carcinoma
G 0.700 GeneticVariation GWASCAT Combined analysis of keratinocyte cancers identifies novel genome-wide loci. 31174203 2019
dbSNP: rs1047840
rs1047840
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0600139
Disease:
Prostate carcinoma
0.010 GeneticVariation BEFREE Our results suggest that CDH1 -160C/A and Exo1 K589E polymorphisms are associated with increased susceptibility to prostate cancer in Bangladeshi population. 30880589 2019
dbSNP: rs1047840
rs1047840
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.010 GeneticVariation BEFREE Our results suggest that CDH1 -160C/A and Exo1 K589E polymorphisms are associated with increased susceptibility to prostate cancer in Bangladeshi population. 30880589 2019
dbSNP: rs1635506
rs1635506
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1629609
Disease:
Age at menopause
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs72755295
rs72755295
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs72755295
rs72755295
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0200638
Disease:
Eosinophil count procedure
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs9350
rs9350
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1168401
Disease:
Squamous cell carcinoma of the head and neck
0.010 GeneticVariation BEFREE This prospective study aimed to investigate whether <i>MLH1</i> c.-93G>A (rs1800734), <i>MSH2</i> c.211+9C>G (rs2303426), <i>MSH3</i> c.3133G>A (rs26279), <i>EXO1</i> c.1765G>A (rs1047840), and <i>EXO1</i> c.2270C>T (rs9350) single nucleotide polymorphisms (SNPs) of the mismatch repair (MMR) pathway change side effects and response rate of 90 HNSCC patients treated with CDDP and RT. 30038702 2018
dbSNP: rs72755295
rs72755295
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0678222
Disease:
Breast Carcinoma
G 0.700 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
dbSNP: rs851797
rs851797
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0919267
Disease:
ovarian neoplasm
0.010 GeneticVariation BEFREE Significant association of the <i>EXO1</i> rs851797 polymorphism with clinical outcome of ovarian cancer. 29042795 2017
dbSNP: rs851797
rs851797
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1140680
Disease:
Malignant neoplasm of ovary
0.010 GeneticVariation BEFREE Significant association of the <i>EXO1</i> rs851797 polymorphism with clinical outcome of ovarian cancer. 29042795 2017
dbSNP: rs851797
rs851797
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C4721610
Disease:
Carcinoma, Ovarian Epithelial
0.010 GeneticVariation BEFREE <i>EXO1</i> rs851797 polymorphism can predict the clinical outcomes in EOC patients. 29042795 2017
dbSNP: rs851797
rs851797
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0677886
Disease:
Epithelial ovarian cancer
0.010 GeneticVariation BEFREE <i>EXO1</i> rs851797 polymorphism can predict the clinical outcomes in EOC patients. 29042795 2017
dbSNP: rs3754093
rs3754093
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C2239176
Disease:
Liver carcinoma
0.010 GeneticVariation BEFREE These results suggest rs3754093 exhibits a protective activity to decrease the incidence risk of HCC in Guangxi, China. 27894089 2016
dbSNP: rs3754093
rs3754093
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0019163
Disease:
Hepatitis B
0.010 GeneticVariation BEFREE According to the results of stratification analysis, rs3754093 mutant genotype AG/GG decreased the risk of HCC with some HCC protective factors such as non-smoking, non-alcohol consumption and non-HCC family history, but also decreased the risk of HCC with HBV infection. 27894089 2016
dbSNP: rs1047840
rs1047840
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.040 GeneticVariation BEFREE For the rs1047840 polymorphism, in an ethnicity subgroup analysis, a significantly increased susceptibility to cancer for Asians was identified in all the genetic models, and for Caucasians in an allelic model. 27387683 2016
dbSNP: rs1047840
rs1047840
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0006826
Disease:
Malignant Neoplasms
0.040 GeneticVariation BEFREE For the rs1047840 polymorphism, in an ethnicity subgroup analysis, a significantly increased susceptibility to cancer for Asians was identified in all the genetic models, and for Caucasians in an allelic model. 27387683 2016
dbSNP: rs10802996
rs10802996
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.010 GeneticVariation BEFREE Our findings provide the evidence that the rs1047840, rs9350, rs10802996, rs1635498, rs1776148, rs1776177, rs3754093 and rs851797 polymorphisms may act as risk factors for cancer. 27387683 2016
dbSNP: rs10802996
rs10802996
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0006826
Disease:
Malignant Neoplasms
0.010 GeneticVariation BEFREE Our findings provide the evidence that the rs1047840, rs9350, rs10802996, rs1635498, rs1776148, rs1776177, rs3754093 and rs851797 polymorphisms may act as risk factors for cancer. 27387683 2016
dbSNP: rs1635498
rs1635498
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0006826
Disease:
Malignant Neoplasms
0.010 GeneticVariation BEFREE Similarly, the rs3754093, rs1776177, rs9350, rs10802996, rs1635498, rs1776148 and rs851797 polymorphisms were also associated with an increased susceptibility to cancer in an allelic model, respectively, while no significant association was identified for rs1635517 polymorphism. 27387683 2016
dbSNP: rs1635498
rs1635498
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.010 GeneticVariation BEFREE Similarly, the rs3754093, rs1776177, rs9350, rs10802996, rs1635498, rs1776148 and rs851797 polymorphisms were also associated with an increased susceptibility to cancer in an allelic model, respectively, while no significant association was identified for rs1635517 polymorphism. 27387683 2016
dbSNP: rs1635517
rs1635517
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0006826
Disease:
Malignant Neoplasms
0.010 GeneticVariation BEFREE Similarly, the rs3754093, rs1776177, rs9350, rs10802996, rs1635498, rs1776148 and rs851797 polymorphisms were also associated with an increased susceptibility to cancer in an allelic model, respectively, while no significant association was identified for rs1635517 polymorphism. 27387683 2016
dbSNP: rs1635517
rs1635517
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.010 GeneticVariation BEFREE Similarly, the rs3754093, rs1776177, rs9350, rs10802996, rs1635498, rs1776148 and rs851797 polymorphisms were also associated with an increased susceptibility to cancer in an allelic model, respectively, while no significant association was identified for rs1635517 polymorphism. 27387683 2016
dbSNP: rs1776148
rs1776148
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0006826
Disease:
Malignant Neoplasms
0.010 GeneticVariation BEFREE Similarly, the rs3754093, rs1776177, rs9350, rs10802996, rs1635498, rs1776148 and rs851797 polymorphisms were also associated with an increased susceptibility to cancer in an allelic model, respectively, while no significant association was identified for rs1635517 polymorphism. 27387683 2016